Thursday, March 31, 2016

I AM MY OWN GUINEA PIG!!! (IAMOGP) -- or eeamogupuh for short.)

Day 6 2mg, twice a day
First Dose at 8AM
Second Dose at about 4PM
Heart Palpitations: None

Thoughts:

Physio/Occu at PPUM, 830AM to 12-ish AM.
20 minutes stationary bike, Wasn't paying attention
15 minutes arm cycling.
3 reps: 2lb Bicep curls x12, front raises x12 ; 4lb shrugs x12
20 minutes leg push thingy but the machine looks like a giant old-skool sewing machine.
30 minute standing with the standing machine.

A bit of a slow, crummy kind of day. Period definitely on the way.

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I AM MY OWN GUINEA PIG!!! (IAMOGP) -- or eeamogupuh for short.)

Day 7 2mg, twice a day
First Dose at 2:15PM
Second Dose at about pm
Heart Palpitations: None

Thoughts: Actually no thoughts today.

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Binge read New Normal: Class 8. It's really good but since I binged it... I HAVE TO WAIT FOR EVERY SUNDAY FOR THE NEXT PIECE. >:(

Tuesday, March 29, 2016

I AM MY OWN GUINEA PIG!!! (IAMOGP) -- or eeamogupuh for short.)

Day 5 2mg, twice a day
First Dose at 12:15PM
Second Dose at about 10pm
Heart Palpitations: None

Thoughts: Not much to comment on today. Stayed at home. I think my period is on the way so legs are taking a bit of a beating and back hurts.

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Okay, I admit to having a soft spot for the dead fat F* Jabba the hutt.
His lines are pretty awesome.

http://www.completewermosguide.com/hutttranscript.html

Monday, March 28, 2016

On to...
I AM MY OWN GUINEA PIG!!! (IAMOGP) -- or eeamogupuh for short.)

Day 4 2mg, twice a day
First Dose at 7:45AM
Second Dose at about 4pm
Heart Palpitations: None

Thoughts:
Physio/Occu at PPUM, 830AM to 10-ish AM.
20 minutes stationary bike, Level 2. Right leg dominant.
15 minutes arm cycling, Level 3 (5m), Level 2 (10m).
3 reps: 2lb Bicep curls x12, front raises x12 ; 4lb shrugs x12
15 minutes leg push thingy but the machine looks like a giant old-skool sewing machine.

The two-pound dumbells were... slightly lighter. Again, I'm not sure if this is all psychosomatic and I'm making all of it up but I'm pretty sure this Salbutamol thing is sort of maybe working.

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On a side note,

Anti-feminist bullshit that is unfounded has made its rounds again -- as it does every year.
Please, read this https://everydaygeopoliticshouston.wordpress.com/2015/04/10/a-reply-to-lauren-southerns-why-im-not-a-feminist/

It is imperative that you go through all the links she provided as well as go through the comments. Just read the entire thing.

Sunday, March 27, 2016

On to...
I AM MY OWN GUINEA PIG!!! (IAMOGP) -- or eeamogupuh for short.)

Day 3: 2mg, twice a day
First Dose at1PM
Second Dose at about 11pm
Heart Palpitations: None

Thoughts: Did not sleep well, not really sure why, maybe taking Salbutamol too late? I don't know.
But I had a mediocre steak... Red meat is still red meat no matter how mediocre it is.

Saturday, March 26, 2016

We now return to...
I AM MY OWN GUINEA PIG!!! (IAMOGP) -- or eeamogupuh for short.)

Day 2: 2mg, twice a day
First Dose at 3PM
Second Dose at about 11pm
Heart palpitations: None

Restlessness: N/A -- I'm taking this out for all future posts because it's not applicable.

Thoughts: I think it needs some sort of benchmark test thingy to be done at the end of the week. Maybe something to do with walking somewhere...

IAMOGP 1

Just wanted to introduce a new segment into this blog called

I AM MY OWN GUINEA PIG!!! (IAMOGP) -- or eeamogupuh for short.) This should be recorded for the appropriate effect.

I have just found out that our friendly neighbourhood asthma drug called Salbutamol (also known as Albuterol and sold as Ventolin) also helps SMA patients to a certain degree. I am elated to know this because of 2 things:

1) It is cheap
2) It is easily accessible

A fellow medical practitioner, let's call himTinkerbell, from the SMA family group recently gave me and a few others instructions for self dosing. He said that optimal dosage for an adult is 4mg, 3 times a day but to start of with 2mg, 3 times a day so that we can check if there are any heartrate issues as it is a stimulant.

Let's discuss how Salbutamol works for a second, this is all from Tinkerbell by the way:
- Salbutamol is a beta 2 agonist. Beta 2 receptors found in lung and heart muscles. Thus incrreasing heart rate and causes bronchiodilation. Since both are muscles, in theory, it will stimulate all muscles.
The main worry is an increased heart-rate, too fast and it will cause an irregular heartbeat (arrythmia) and the Respiratory specialists will say that it can cause ventilation/perfussion missmatch.

- If you get heart palpitations, drink plenty of water -- I'm guessing it helps you pee out the drugs.
Lower dosage if palpitations happen.

- Optimum dosage would be 4mg, 3 times a day (based on my weight apparently) but to keep things safe, start with 2mg, every 8hours.

And now, some research of my own as to the effects of Salbutamol on SMA...
- (http://www.ncbi.nlm.nih.gov/pubmed/20837492)
METHOD:
Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by mutations of the SMN1 gene. Based on severity, three forms of SMA are recognised (types I-III). All patients usually have 2-4 copies of a highly homologous gene (SMN2) which produces insufficient levels of functional survival motor neuron (SMN) protein. Recently, evidence has been provided that SMN2 expression can be enhanced in vitro by salbutamol, a β2-adrenergic agonist. This compound has also been shown to improve motor function of SMA patients in two different pilot trials.
RESULTS:
A significant and constant increase in SMN2 full length transcript levels was detected; the response was directly proportional to SMN2 gene copy number.

- Salbutamol for Spinal Atrophy Type 3 
CONCLUSION:
Oral salbutamol has been well tolerated and appears to maintain, and in some cases improve motor performance in SMA III

(Click links for further readings and do a quick Google search for more info)
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Bought Salbutamol from pharmacy.21 tablets (2mg each) costs RM4.20,ergo, cheap as chips. 21 tablets for a one week test, starting tomorrow. I think I'll be doing voice recordings on my thoughts and the effects.

Day 1: 2mg, twice a day
First Dose at 2:14PM
Second Dose at about 10pm
Heart palpitations: None

Restlessness: The usual amount because i have never had a day where I just sit and do nothing.

Thoughts: It's probably psychosomatic but I feel a tad better. Also, keep in mind that I did have an intense work-out session yesterday (Weights went up from 3lb to 4lb -- it's not much for you but it's satan on my muscles) so it might be my body's just chilling out and fixing itself.

Thursday, March 03, 2016

It's almost 4AM... I had coffee late... hahahaha

Alfred posted this so now I'm reposting it... Because I ain't sleepy.

Here are the rules for you to ignore or adhere to as you see fit: (copy & paste) in your status update, list 12 albums that have stayed with you (whatever that brings to mind for you) - but, and this is the most important rule/non-rule only 1 per band/artist. Don't take too long and no need to think too hard. Tag ten Facebook friends (including me) and get them to do the same thing. We'll leave compilation albums out please. Happy reminiscing!

Also, mind, I'm not tagging (nor did I tag) anyone and this one will have a long story about why these albums stuck with me and only the ones where I love THE ENTIRE album. These made the cut.

1. QUEEN's Greatest Hits
This one's easy. It's the first album gifted to me by the fathur when I was in grade 1. Stuck with me forever.

2. QUEENThe Crusader's Chain Reaction
Possible Introductory album to Jazz/Funk, rifled through the fathur's music stash. NO RAGRETSSSS

3. TUPAC's Until The End Of Time
I have a soft spot for Gangsta Rap. Also, I'm like the least OG person ever. hahahaha

4. INCUBUS' A Crow Left Of The Murder
I. LOVE. INCUBUS. And I hate that I can't list down their entire discography

5. BONE THUGS 'N' HARMONY's The Art Of War
The amount of times I listened to this was incredible... I even memorised EVERY song and rapped along to it. I know, right? What?

6. KORN's Untouchables
This album was cathartic to 14 year old Sha.

7. SYSTEM OF A DOWN's Steal This Album!
This album was hilarious and bouncy to late teens Sha

8. SOUNDGARDEN's Superunknown
Better than Nirvana on all fronts. Hands down.

9. DETHKLOK's Dethalbum (because lol)
Seriously, Branden Smalls is amazing. Want. Also because I love Metalocalypse.

10. CAMILLE's Le Sac De Filles
Hello, Bossa Nova and awesome stage music live things!

11. SEVEN COLLAR T-SHIRT's Drones
Yes. Just yes.

12. GTA: ST ANDREAS, K-DST Radio channel. (Does this even count? It does now haha)
Little Brother played GTA:SA so much that this channel is embedded in my brain. Comedy gold is my fathur reacting to this...
"Pak hitam listening to white rock. hahahahahaha"